Protein Details: Aquaglyceroporin

Protein ID

ICDB_Pro_0016

Protein Name

Aquaglyceroporin

Gene Name

AQP; PBANKA_0915600

Organism

Plasmodium berghei (strain Anka)

Length

258 amino acids

AlphaFoldDB

AF-A0A509APT1-F1-model_v4.pdb

Function

Mediates water and glycerol transport across the cell membrane. Permeable to urea. Required for efficient progression of parasites through the liver stages.

Sequence

MKVTFGNEYIKNFLGEFIGTFVLMFLGEGTTANHFAVPIKNDWLRLCIGWGLGVFFGILISAKLSGAHLNLAVTVGLSTIKKFNYKQIPLYFAGQLLGALSATASVYGLYYGFVSDQTIPKFSWETGKHANVHIASAFMHEFILTGILLLIILSVTDENICGKFHVLKVSSIVGLAIICIGISFGGNTGFALNPSRDLGARILSAIAYGFEAFTRDKCYFWIPLIAPIIGSIIFCQIYDKIVAPLVVISEHDKGALEI

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1186/s12915-014-0086-0; 10.1073/pnas.0610843104; 10.1038/s41598-017-18987-3

RefSeq

XP_675187.1; XP_676524.1